Sona Vasudevan


SOM Medical Educator Track -- Professor
Director, dual-degree program (MD/MS) and MS program in Systems Medicine; Adjunct Senior Bioinformatics Scientist, Protein Information Resource (PIR)


Biochemistry and Molecular and Cellular Biology
General profile


+1 202-687-2242


LR3 Harris Building


Dr. Vasudevan was trained in the labs of Dr. Zaverio Ruggeri (Head, Department of Experimental Medicine) at the Scripps Research Institute, and Dr. Tom Cech (Nobel Laureate) at the University of Colorado. Prior to joining Georgetown, she worked at the National Institutes of Health (NIH) – she was a Visiting Scientist in the lab of Dr. David Davies (memeber of the National Academy of Sciences) at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and a Bioinformatics Scientist in the groups of Dr. Eugene Koonin and Dr. Steve Bryant at the National Center for Biotechnology Information (NCBI).

Dr. Vasudevan is skilled in the areas of structural biology, structural bioinformatics, homology modeling, protein-ligand and antibody-antigen interactions, and RNA biology. She is spear-heading a novel approach, called “ligand-centric”, for functional prediction using 3D-structural information. Her research interests include comparative genomics, protein classification, protein homology modeling, and molecular dynamics simulations to look at the effect of single nucleotide polymorphisms in breast cancer, evolutionary analysis, systems biology, and translational informatics. She has contributed to the development of several well-known bioinformatics tools for doing sequence and structure analysis during her tenure at NCBI and the Protein Information Resource. Based on her “ligand-centric” approach she has developed LigFam, a drug-discovery database. Her research record includes several research papers, invited lectures, and book chapters. She serves on the Editorial Board of, and is a reviewer for, several journals.

She teaches Biochemistry, Structural Biology, and several courses in Informatics. She has mentored over 20 students. She has created the MD/MS dual-degree program in Systems Medicine, which is one of its kind in the field (

She has received several awards including the Dahlgren Memorial Library’s READ POSTER Honoree for Contribution to Cura Personalis, excellence-in-teaching awards, the Howard Hughes Research Fellowship, the Skaggs Research Fellowship (Scripps Research Institute), and the International Human Frontier Science Program Long-term Post-doctoral Fellowship.


  • Ph.D. (Medical Biophysics) University of Toronto, Canada