Manus M. Patten
Title
Main Campus Non-Ordinary - Instructional F
Laboratory Assistant Professor
Laboratory Assistant Professor
Department
Department of Biology
Research
Research
Sex-specific selection: In most species there are two sexes that may not experience the same selection pressures. I explore the theoretical consequences of these simple facts on a number of fronts. I examine how gene frequencies change and how genomic architecture evolves when selection differs between the sexes.
Parent-of-origin-specific selection: As sure as sex-specific selection can exist in a population with two sexes, so too can parent-of-origin-specific selection. The optimal allele in one parent-of-origin context may not be the optimal allele in the other parent-of-origin context, creating parental antagonism. This is a relatively unexplored form of selection that may favor the evolution of genomic imprinting and other hereditary phenomena.
Sexual dimorphism for gene expression: A wealth of data shows that genes are expressed at different levels in the two sexes. My research investigates whether these data fit any theoretical predictions from available sex-specific selection models and whether our current theory encompasses all possibilities.
Parent-of-origin-specific selection: As sure as sex-specific selection can exist in a population with two sexes, so too can parent-of-origin-specific selection. The optimal allele in one parent-of-origin context may not be the optimal allele in the other parent-of-origin context, creating parental antagonism. This is a relatively unexplored form of selection that may favor the evolution of genomic imprinting and other hereditary phenomena.
Sexual dimorphism for gene expression: A wealth of data shows that genes are expressed at different levels in the two sexes. My research investigates whether these data fit any theoretical predictions from available sex-specific selection models and whether our current theory encompasses all possibilities.