Zhang-Zhi Hu joined Lombardi in November 2008 as tenure track Associate Professor in the Department of Oncology. He received his MD from Wannan Medical College and MS from Beijing Medical University, China. Before joining Lombardi, he was Research Associate Professor at the Protein Information Resource (PIR), Department of Biochemistry and Molecular & Cellular Biology at Georgetown, where his research focused on functional analyses of large-scale gene expression and proteomic data and development of bioinformatics tools and resources for such analysis. He worked as a postdoctoral and subsequently a research fellow at the National Institute of Child Health and Human Development, where he studied molecular mechanisms underlying the prolactin receptor gene regulation and received a Fellows Award for Research Excellence. At Lombardi, he focuses on biological pathway and network analysis and modeling of cancer omics data for identification of molecular targets to improve cancer diagnosis, prognosis and therapeutic development. Specifically he is modeling the estrogen-induced apoptosis pathways in hormone resistant breast cancer cells, ATM-mediated radiation-induced DNA damage repair pathway, and protein O-GlcNAcylation/ phosphorylation networks in cancer.