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Cynthia Marie Rosenthal

Title

Associate Professor on the Medical Educator Track
Director, M.S. Biochemistry and Molecular Biology program

Department

Biochemistry and Molecular and Cellular Biology
Research

Research

My current research interests revolve around the roles of specific genes in molecular mechanisms of apoptosis, a form of cellular suicide important in both normal development and a number of human diseases, as well as the practical aspects of modulating this process in the development of therapeutic approaches to cancer, autoimmune, and neurodegenerative diseases, such as Parkinson’s Disease. Abnormalities in apoptotic regulation have been shown to play a critical role in pathogenesis of these diseases.
Recent research efforts have been focused on the roles of Inhibitor-of-DNA binding (Id) family proteins (Id1-Id4) in apoptosis, proliferation, skin tumorigenesis and melanomagenesis. A new direction that we have started to explore is the isolation, growth, characterization and targeting of cancer stem cells or tumor initiating cells from patient-derived melanomas.