Priscilla A Furth
Title
Professor
Professor, Departments of Oncology and Medicine
Professor, Departments of Oncology and Medicine
Department
Lombardi Comprehensive Cancer Center (LCCC)
Publications
Publications
Articles in journals
- Miermont AM, Parrish AR, Furth PA.. "Role of ER{alpha} in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis." Carcinogenesis 6 (2010): 1124-31.
- Díaz-Cruz ES and Furth, PA. "Deregulated estrogen receptor alpha and p53 heterozygosity collaborate in the development of mammary hyperplasia." Cancer Research 70 (2010): 3965-74.
- Cheema A, Knights CD, Rao, M, Catania J, Perez R, Simons B, Dakshanamurthy S, Kolukula VK, Tilli M, Furth PA, Albanese C and Avantaggiati ML. "Functional Mimicry of the acetylated C-terminal Tail of p53 by a SUMO-1 Acetylated Domain, SAD." Journal of Cellular Physiology 225 (2010): 371-84.
- Kleinberg DL, Wood TL, Furth PA, Lee AV.. "Growth Hormone and Insulin-Like Growth Factor-I in the Transition from Normal Mammary Development to Preneoplastic ." Endocr Rev 30 (2009): 51-74.
- Frech, MS, Torre, K, Robinson, G and Furth PA. "Loss of cyclin D1 in concert with deregulated Estrogen Receptor alpha expression in the mammary gland induces upregulation of cyclin E and a DNA damage response.." Cancer Research 27 (2008): 3186-93.
- Fereshteh, M, Tilli, MT, Kim, B, O’Malley, B, Xu, J, Wellstein, A, Furth, PA and Riegel, AT. . "The Nuclear Receptor Coactivator Amplified in Breast Cancer-1 is required for Neu (ErbB2/HER2) activation, signaling and mammary tumorigenesis in mice.." Cancer Research 68 (2008): 3697-706.
- Jones, LP, Tilli, MT, Assefnia, S, Torre, K, Halama, ED, Parrish, A, Rosen EM, and Furth, PA. . "Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha negative and ERalpha positive mammary preneoplasia and cancer." Oncogene 27 (2008): 794-802.
- Tilli, MT, Cabrera, MC, Parrish, AR, Torre, KM, Sidawy, MK, Gallagher, AL, Makariou, E, Polin, SA, Liu, MC and Furth, PA. "Real-Time Imaging and Characterization of Human Breast Tissue by Reflectance Confocal Microscopy." Journal of Biomedical Optics (2007).
- Herschkowitz, J., Simin, ., Weigman, VJ, Mikaelian, I, Usary, J, Hu, Z, Rasmussen, KE, Jones, LP, Assefnia, S, Chandrasekharan, S, Backlund, MG, Yin, Y, Khramtsov, AI, Glazer, RI, Brown, PH, Green,. "Identification of conserved gene expression features of murine breast carcinoma models relative to each other and to human cancers." Genome Biology 8 (2007): R76.
- Greenfeld, CR, Pepling, ME, Babus, JK, Furth, PA and Flaws, JA. "BAX Regulates Follicular Endowment in Mice." Reproduction 133 (2007): 865-76.
- Tomic D, Frech MS, Babus JK, Symonds D, Furth PA, Koos RD, Flaws JA. "Effects of ERalpha overexpression on female reproduction in mice." Reprod Toxicol. 23 (2007): 317-25.
- Tomic, D, Frech, MS, Babus, JK, Gupta, RK, Furth, PA, Koos, RD, Flaws. JA. "Methoxychlor Induces Atresia of Antral Follicles in ERa Overexpressing Mice." Toxicological Sciences 93 (2006): 196-204.
- Greenfeld, CR, Babus, JK, Furth, PA, Marion, S, Hoyer, PB, and Flaws, JA.. "BAX is Involved in Regulating Follicular Growth, but is Dispensable for Follicle Atresia in Adult Mouse Ovaries." Reproduction 133 (2006): 107-116.
- Katiyar, P, Ma, Y, Fan, S, Pestell, RG, Furth, Rosen, EM. . "Regulation of Progesterone Receptor Signaling by BRCA1 in Mammary Cancer.." Nuclear Receptor Signaling 4 (2006): e006 .
- Furth, PA., Ma, Y., Katiyar, P., Jones, LP., Fan, S., Zhang, Y., & Rosen, EM. "The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells." Molecular Endocrinology 20.1 (2006): 14-34.
- Furth, PA., Bachelier, R., Xu, X., Li, C., Qiao, W., Lubet, RA., & Deng, CX. "Effect of bilateral oophorectomy on mammary tumor formation in BRCA1 mutant mice." Oncology Reports 14.5 (2005): 1117-20.
- Frech, MS, Jones, LP and Furth, PA. "Validation of transgenic models of breast cancer: Ductal Carcinoma In Situ (DCIS) and Brca1 mutation-related breast cancer." Breast Cancer Online 8 (2005): 8.
- Jones, LP, Li, M, Halama, ED, Ma, Y, Lubet, R, Grubbs, CJ, Deng, C-X, Rosen, EM and Furth, PA. "Promotion of mammary cancer development by tamoxifen in a mouse model of Brca1. ." Oncogene 24 (2005): 3554-3562.
- Tilli, MT, Reiter, R, Oh, AS, Henke, RT, McDonnell, K, Gallicano, GI, Furth, PA, Reigel, AT. "Overexpression of an N-terminally truncated isoform of the nuclear receptor coactivator AIB1/ACTR leads to altered proliferation of mammary epithelial cells in transgenic mice." Molecular Endocrinology 19 (2005): 644-656.
- Abaan, OD, Levenson, A, Khan, O, Furth, PA, Üren, A and Toretsky, JA. . "PTPL1 is a Direct Transcriptional Target of EWS-FLI1 and Modulates Ewing’s Sarcoma Tumorigenesis." Oncogene 24 (2005): 2715-2722.
- Frech, MS, Halama, ED, Tilli, MT, Singh, B, Gunther, EJ, Chodosh, LA, Flaws, JA and Furth, PA. "Deregulated Estrogen Receptor alpha Expression in Mammary Epithelial Cells of Transgenic Mice Results in the Development of Ductal Carcinoma In Situ." Cancer Research 65 (2005): 681-685.
- Parrish, A, Halama, E, Tilli, MT, Freedman, F and Furth, PA. . "Reflectance Confocal Microscopy for Characterization of Mammary Ductal Structures and Development of Neoplasia in Genetically Engineered Mouse Models of Breast Cancer.." Journal of Biomedical Optics 10 (2005): 51602-8.
- Jamerson, MH, Johnson, MD, Korsmeyer, SJ, Furth, PA and Dickson, RB. "Bax regulates c-Myc-induced mammary tumor apoptosis but not proliferation in MMTV-c-myc transgenic mice. ." Br J Cancer 91 (2004): 1372-1379.
- Tilli, MT, Hudgins, SL, Frech, MS, Halama, ED, Renou, J-P, and Furth, PA. . "Loss of PP2A Expression Correlates with Phosphorylation of DP-1 and Reversal of Dysplasia through Differentiation in a Conditional Mouse Model of Cancer Progression. ." Cancer Research (2003).
- Tilli, MT, Frech, MS, Steed, ME, Hruska, KS, Johnson, MD, Flaws, JA, and Furth, PA. . "Introduction of ERa into the tTA/Tag conditional model precipitates the development of estrogen responsive mammary adenocarcinoma.." American Journal of Pathology 163.5 (2003).
- Cotarla, I+, Ren, S+, Zhang, Y, Gehan, E, Singh, B and Furth, PA. "Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers.." International Journal of Cancer (2003).
- Xu, X, Aprelikova, O, Moens, P, Deng, CX and Furth, PA.. "Impaired meiotic DNA damage repair and lack of crossing over during spermatogenesis in BRCA1 full-length isoform deficient mice. ." Development 130 (2003): 2001-2012.
- Li, M, Ren, S, Tilli, MT, Flaws, JA, Lubet, R, Grubbs, CJ and Furth, PA. "Chemoprevention of mammary carcinogenesis in a transgenic mouse model by a-Difluoromethylornithine (DFMO) in the diet is associated with decreased cyclin D1 activity. ." Oncogene 22 (2003): 2568-2572.
- Maddalena T Tilli and Priscilla A Furth. "Conditional mouse models demonstrate oncogene-dependent differences in tumor maintenance and recurrence.." Breast Cancer Research 5 (2003): 202-205.
- Clevenger, CV, Furth, PA, Hankinson, S and Schuler, L. . "The role of prolactin in mammary carcinoma. ." Endocrine Reviews 24 (2003): 1-27.