Claudine Janet Diana Isaacs


Co-Director, Breast Cancer Program
Medical Director, Fisher Center for Hereditary Cancer and Clinical Genomics Research


Breast Cancer
General profile



+1 202-444-3677


Dr. Claudine Isaacs is a Professor of Medicine and Oncology and the co-Director of the Breast Cancer Program at the Lombardi Comprehensive Cancer Center (LCCC) at Georgetown University. She is also the Medical Director of the Jess and Mildred Fisher Center for Familial Cancer Research. Dr. Isaacs received her medical degree and residency training at McGill University. She completed fellowship training in the Division of Hematology and Oncology at McGill University and a Fellowship in Breast Medical Oncology in the Division of Medical Oncology at Georgetown University. She then joined the faculty in the Department of Medicine and Oncology at Georgetown University.

Dr. Isaacs has extensive experience in the conduct of clinical trials focusing on all aspects of breast cancer. Additional research interests include cancer risk assessment and medical management and prevention strategies for women at high risk for breast cancer. She has served as the PI of a variety of clinical trials in treatment of early-stage and metastatic breast cancer, and served as the PI of the Cancer Genetics Network site and the PLCO Trial at Georgetown University. She has authored over 170 peer reviewed publications. She has served on a number of committees including the Cancer Education Committee at ASCO, the ASCO Scientific Program Committee and is a member of the Breast Oncology Local Diseases Task Force of the Breast Steering Committee of the NCI. She has been named one of America's Top Cancer Doctors by Castle Connolly/Newsweek for many years running, and has also received designations from Washingtonian Magazine and Women's Health Magazine.


  • Fellowship (1993) Div. Medical Oncology, Georgetown Univ. Med. Cen., Breast Cancer
  • Residency/Fellowship Training (1992) McGill University, Montreal, Quebec, Canada, Hematology and Medical Oncology
  • Residency Training (1990) Montreal General Hospital, McGill Univ., Montreal, Internal Medicine
  • MDCM (1987) McGill University,
  • BSc (1983) McGill University, Montreal, Quebec, Great distinction in biol., majors in human gene.


  • French (speak, read, write)