Eliot M Rosen




Breast Cancer
General profile


Research Building


Dr. Rosen was recruited to the Lombardi Comprehensive Cancer Center (LCCC)/Georgetown University in 2003, where he is currently Professor of Oncology, Biochemistry and Cell & Molecular Biology, and Radiation Medicine (Tenured). He holds the Gragnani Chair in Oncology and Radiation Biology. He is also Co-Director of the Radiobiology and DNA Repair Program of the LCCC. Dr. Rosen is an experienced cell and molecular biologist. His major areas of interest include the molecular function of the breast cancer susceptibility gene-1 (BRCA1) in DNA repair pathways; the role of BRCA1 in regulating the activity of several nuclear receptors (including the estrogen and progesterone receptors); its role in cancer chemoprevention; and signal transuction pathways of scatter factor (hepatocyte growth factor) and its receptor c-Met that leads leads to protection against apoptosis and chemo/radioresistance of tumors. These studies have relevance to breast cancer, prostate cancer, and primary brain tumors (gliomas and glioblastomas).

In addition to being a research scientist, Dr. Rosen is a board-certified Radiation Oncologist and has many years of experience in the clinical management of various types of tumors, including breast cancer, prostate cancer, brain tumors, and other tumor types. Thus he is very well familiar with the natural history of these cancers and their responses to therapy.


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  • Residency (1984) Joint Center, Harvard Medical School, Radiation Therapy
  • Internship (1981) Beth Israel Hospital, Harvard Medical School, Medicine
  • PhD (1980) University of Pennsylvania, Physiology (Cellular)
  • MD (1979) University of Pennsylvania, Medicine
  • MS (1974) Massachusetts Institute of Technology, MA, Chemical (Biomedical) Engineering
  • BS (1972) Columbia University, NY, Chemical Engineering