George B Chapman
Department of Biology
Studies of cell structure and ultrastructure are pursued to expand on our knowledge in these areas basically, to relate structural discoveries to functional matters, and, with experimental procedures, to determine how changed structure may relate to changed function. Our laboratory has investigated structures varying from viruses to humans. Our most significant contributions to the field of ultrasructure include the first successful preparation of ultrathin sections of vegetative bacteria, studies of the nematocysts of Hydra, studies on the behavior of the bacterial cytoplasmic membrane during cellular division, studies of the insect nervous system, clarification of the nature of the figures of Eberth in the anuran epidermis, discovery of myelinated nerves in the cores of the trabeculae of the human eye, structure of viruses in cells of the human wart, ultrastuctural changes of bacteria following exposure to antibiotics , studies of human and whale blood cells, structure of marine bacteriophage, studies of the ultrastructural features of protozoa and algae, studies of Dufour's gland in insects, and discovery of a new inclusion body in a rat renal cell. These studies have produced electron micrographs used as illustrations in more than 30 textbooks, ranging from general biology and microbiology to general botany, bacterial physiology, phycology, fish histology, parasitology, and biochemistry.