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Publications
PublicationsArticles in journals- Sanjay Adhikari, Aykut Üren, and Rabindra Roy. "N-Terminal Extension of N-Methylpurine-DNA Glycosylase is Required for Turnover in Hypoxanthine Excision Reaction." Journal of Biological Chemistry (2007).
- Jeffrey A. Toretsky, Verda Erkizan, Amy Levenson, Ogan D. Abaan, Jeffrey D. Parvin, Timothy P. Cripe, Anna M. Rice, Sean Bong Lee and Aykut Üren. "Oncoprotein EWS-FLI1 activity is enhanced by RNA Helicase A (RHA)." Cancer Research 66 (2006): 5574-5581.
- Dave N.T. Arye, Michael Kreppel, Radostina Bachmaier, Aykut Üren, Karin Muehlbacher, Stefan Wagner, Heimo Breiteneder, Jozef Ban, Jeffrey A. Toretsky and Heinrich Kovar. "Single-chain antibodies to the EWS NH2 terminus structurally discriminate between intact and chimeric EWS in Ewing’s sarcoma and interfere with transcriptional activity of EWS in-vivo." Cancer Research 66 (2006): 9862-9869.
- Yoshimi Endo, Vladimir Wolf, Kanae Muraiso, Keiju Kamijo, Aykut Üren, Michal Barshishat-Kupper and Jeffrey S. Rubin. "Wnt-3a-Associated Cell Motility Involves RhoA Activation and is Specifically Regulated by Dishevelled-2." Journal of Biological Chemistry 280.1 (2005): 777-86.
- Aykut Üren, and Jeffrey A. Toretsky. "Pediatric Malignancies Provide Unique Cancer Therapy Targets." Current Opinion in Pediatrics 17.1 (2005): 14-19.
- Ogan Abaan, Amy Levenson, Osman Khan, Priscilla Furth, Aykut Üren, and Jeffrey A. Toretsky. "PTPL1 is a Direct Transcriptional Target of EWS/FLI1 and Modulates Ewing’s Sarcoma Tumorigenesis." Oncogene 24.16 (2005): 2715-22.
- Aykut Üren (Corresponding Author), Shannon Fallen, Hang Yuan, Alp Usubütün, Türkan Küçükali, Richard Schlegel, and Jeffrey A. Toretsky. "Activation of the canonical Wnt pathway during genital keratinocyte transformation: a model for cervical cancer progression." Cancer Research 65 (2005): 6199-6206.
- Aykut Üren (Corresponding Author), and Jeffrey A. Toretsky. "EWS-FLI1 oncoprotein, an elusive target waiting to be hit in Ewing’s Sarcoma patients." Future Oncology 1.4 (2005): 521-528.
- Jeffrey A. Toretsky, Amy Levenson, Irvin N. Weinberg, Jonathan F. Tait, Aykut Üren, and Ronald C. Mease. "Preparation of F-18 labeled annexin V: a potential PET radiopharmaceutical for imaging cell death." Nuclear Medicine and Biology 31.6 (2004): 747-752.
- Aykut Üren (Corresponding Author), Vladimir Wolf, Yoshimi Endo, Yu-Feng Sun, Amir Azari, Jeffrey S. Rubin, Jeffrey A Toretsky. "Wnt/Frizzled signaling in Ewing sarcoma." Pediatric Blood and Cancer 43.3 (2004): 243-9.
- Aykut Üren (Corresponding Author), Olga Tcherkasskaya, and Jeffrey A. Toretsky. "Recombinant EWS-FLI1 oncoprotein activates transcription." Biochemistry 43.42 (2004): 13579-13589.
- Yoshiro Chuman, Aykut Üren, Jennifer Cahill, Carole Regan, Vladimir Wolf, Brian K. Kay, and Jeffrey S. Rubin. "Identification of a Novel Binding Motif for Secreted Frizzled-Related Protein-1 by Peptide Phage Display Analysis." Peptides 25.11 (2004): 1831-1838.
- Aykut Üren (Corr. Auth.), Melinda S. Merchant, Chen-Chih J. Sun, Michele Vitolo, Yu-Feng Sun, Maria Tsokos, Peter B. Illei , Marc Ladanyi, Antonino Passaniti, Crystal Mackall, Jeffrey A. Toretsky. "Beta-Platelet Derived Growth Factor Receptor Mediates Motility and Growth of Ewing’s Sarcoma Cells." Oncogene 22.15 (2003): 2334-2342.
- Jae Min Chong, Aykut Üren, Jeffrey S. Rubin, and David W. Speicher. "Disulfide bond assignments of secreted frizzled related protein-1 provide insights about frizzled homology and netrin modules." Journal of Biological Chemistry 277.7 (2002): 5134-5144.
- Kiyoshi Yoshino, Jeffrey S. Rubin, Kathleen G. Higinbotham, Aykut Üren, Vasiliki Anest, Sergei Y. Plisov and Alan O. Perantoni . "Secreted Frizzled-related proteins can regulate metanephric development." Mechanisms of Development 102.1-2 (2001): 45-55.
- Aykut Üren, Frieda Reichsman, Vasiliki Anest, William G. Taylor, Kanae Muraiso, Donald P. Bottaro, Susan Cumberledge, and Jeffrey S. Rubin. "Secreted frizzled-related protein-1 binds directly to wingless and is a biphasic modulator of Wnt signaling." Journal of Biological Chemistry 275.6 (2000): 4374-4382.
- Angela Panoskaltsis-Mortari, Patricia A. Taylor, Jeffrey S. Rubin, Aykut Üren, Lisbeth A. Welniak, William J. Murphy, Catherine L. Farrel, David L. Lacey, Bruce R. Blazar. "Keratinocyte growth factor (KGF) facilitiates alloengraftment and ameliorates GVHD in mice by a mechanism independent of repair of conditioning-induced tissue injury." Blood 96.13 (2000): 4350-4356.
- Aykut Üren, Jin-Chan Yu, Musturay Karcaaltincaba Jacalyn H. Pierce, Mohammad A. Heidaran. "Oncogenic activation of the alpha-PDGFR identifies a domain that negatively regulates receptor dimerization." Oncogene 14.2 (1997): 157-162.
- Marco Lopez-Ilasaca, Weiqun Li, Aykut Üren, Jin-Chan Yu, Andrius Kazlauskas, Silvio Gutkind, Mohammad A. Heidaran. "Requrement of phosphatidylinositol-3 kinase for activation of JNK/SAPKs by PDGF." Biochemical and Biophysical Research Communication 232.2 (1997): 273-277.
- Paul W. Finch, Xi He, Michael J. Kelley, Aykut Üren, Paul Schaudies, Nicholas C. Popescu, Stuart Rudikoff, Stuart A. Aaronson, Harold E. Varmus, and Jeffrey S. Rubin. " Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action." Proc. Natl. Acad. Sci. USA 94.13 (1997): 6770-6775.
- Aykut Üren, Judit Jakus, Jaime Font de Mora, Andrew Yeudall, Eugenio Santos, Silvio Gutkind, Mohammad A. Heidaran. "Carboxy terminal domain of p27Kip1 activates cdc2." Journal of Biological Chemistry 272.35 (1997): 21669-21672.
- Jaime Font de Mora, Aykut Üren, Mohammed A. Heidaran, Eugenio Santos. "Biological activity of p27kip1 and its amino- and corboxy- terminal domains in G2/M transition of Xenopus oocytes." Oncogene 15.21 (1997): 2541-2551.
- Aykut Üren, Jin-Chen Yu,Weiquin Li, Il-Yup Chung, Daruka Mahadevan, Jacalyn H. Pierce and Mohammad A. Heidaran. " Identification of a domain within the carboxy-terminal reagion of beta-PDGFR that mediates the high transforming activity of PDGF." Journal of Biological Chemistry 271.19 (1996): 11051-11054.
- Jin-Chan Yu, Weiqun Li, Ling-Mei Wang, Aykut Üren, Jacalyn H. Pierce, and Mohammed A. Heidaran. "Differential requirement of a motif within the carboxy terminal domain of alpha-PDGFR for PDGF focus forming activity chemotaxis, or growth.." Journal of Biological Chemistry 270.13 (1995): 7033-7036.
- Daruka Mahadevan, Jin-Chan Yu, Jose W. Saldanha, Narmada Thanki, Peter McPhie, Aykut Üren, William J. LaRochelle and Mohammad A. Heidaran. "Structural role of extracellular domain 1 of alpha -Platelet Derived Growth Factor Receptor for PDGF-AA and PDGF-BB binding." Journal of Biological Chemistry 270.46 (1995): 27595-27600.
- Aykut Üren, Jin-Chan Yu, Nahid S. Gholami, Jacalyn H. Pierce, and Mohammad A. Heidaran. "The alpha-PDGFR tyrosine kinase mediates locomotion of two different cell types through chemotaxis and chemokinesis.." Biochemical and Biophysical Research Communication 204.2 (1994): 628-634.
- Aykut Üren, Wayne E. Criss. "Platelet Derived Growth Factor; A review of oncogene-growth factor-cancer relationship.." Turkish Journal of Cancer 23.1 (1993): 5-16.
- Ali Ayhan, Hakan Yarali, Osman Develioglu, Aykut Üren, Filiz Ozyilmaz. "Prognosticators of second-look laparotomy findings in patients with epithelial ovarian cancer.." Journal of Surgical Oncology 46.4 (1991): 222-225.
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